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KMID : 0364820120480040305
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Korean Journal of Microbiology
2012 Volume.48 No. 4 p.305 ~ p.308
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Antifungal and Antioxidant Activities of Volatile Organic Compounds Generated During the Drying Process of Chamaecyparis obtuse
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Seo Young-Jun
Lee Jae-Won
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Abstract
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In this study, we evaluated antifungal and antioxidant activities of condensed liquid of volatile organic compounds
generated during the drying process of Chamaecyparis obtuse. Condensed liquid of volatile organic compounds
were extracted with hexane and ethyl acetate, respectively. The extracts were used for antifungal activity at range
from 100 to 500 mg/L Antifungal activity of extracts increased as the extracts concentration increased, the activity
against tested dermatophytes was high at 500 mg/L. Among extract solvents, antifungal activity was higher at
hexane extract than the ethyl acetate. Especially, the antifungal activity against Trichophyton rubrum was higher than
other tested dermatophytes. Antioxidant activity was 90% above 25 mg/L regardless of the extractive solvents, while
the hexane extract showed high antioxidant activity below 25 mg/L. Major compounds of hexane extract were
torreyol, alpha-cadinol, and tau-cadinol. However, major compounds of ethyl acetate extract were alpha-amorphene,
alpha-cadinol, and gamma-cadinene.
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KEYWORD
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Chamaecyparis obtuse, antifungal activity, antioxidant activity, drying process, volatile organic compounds
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